Publications

§ = shared first; * = corresponding

S. Schmid*, C. Dekker*

The NEOtrap – en route with a new single-molecule technique.

iScience (2021) accepted.

S. Schmid, P. Stömmer, H. Dietz, C. Dekker

Nanopore electro-osmotic trap for the label-free study of single proteins and their conformations.

Nature Nanotechnology (2021). [preprint]

J. Alfaro§, P. Bohländer§ ,Filius§, C.J. Howard§, X. van Kooten§, S. Ohayon§, A. Pomorski§, S. Schmid§, S.H. Kim, P. Samaras, B. Kuster, G. Bedran, M. Wilhelm, L. Sepiashvili, U. Kalathiya1, S. Kumar, A. Aksimentiev, D. Stein, N. Drachman, D. Goodlett, C. Masselon, S. Hentz, M. Chinappi, C. Chan, M. Mayer, S. Lindsey, D. Rodriguez Larrea, E.M. Marcotte, G. Maglia, G. Dittmar, J. Marino, Z. Kelman, M. Wanunu, N.L. Kelleher, R. Eelkema, P. Yin, E.V. Anslyn, C. Dekker, A. Meller, C. Joo.

The emerging landscape of single-molecule protein sequencing technologies.

Nature Methods, 18, 604–617 (2021). [pdf]

S. Schmid*, C. Dekker*.

Nanopores: a versatile tool to study protein dynamics.

Essays in Biochemistry, EBC20200020, (2020). [preprint]

S. Schmid* & T. Hugel*.

Controlling protein function by fine-tuning conformational flexibility

eLife , e57180 (2020). [pdf]

A. Fragasso, S. Schmid & C. Dekker.

Comparing current noise in solid-state and biological nanopores.

ACS Nano 14, 1338-1349 (2020). [pdf]

Björn Hellenkamp§, Sonja Schmid§, Olga Doroshenko, Oleg Opanasyuk, Ralf Kühnemuth, Soheila Rezaei Adariani, Benjamin Ambrose, Mikayel Aznauryan, Anders Barth, Victoria Birkedal, Mark E. Bowen, Hongtao Chen, Thorben Cordes, Tobias Eilert, Carel Fijen, Christian Gebhardt, Markus Götz, Giorgos Gouridis, Enrico Gratton, Taekjip Ha, Pengyu Hao, Christian A. Hanke, Andreas Hartmann, Jelle Hendrix, Lasse L. Hildebrandt, Verena Hirschfeld, Johannes Hohlbein, Boyang Hua, Christian G. Hübner, Eleni Kallis, Achillefs N. Kapanidis, Jae-Yeol Kim, Georg Krainer, Don C. Lamb, Nam Ki Lee, Edward A. Lemke, Brié Levesque, Marcia Levitus, James J. McCann, Nikolaus Naredi-Rainer, Daniel Nettels, Thuy Ngo, Ruoyi Qiu, Nicole C. Robb, Carlheinz Röcker, Hugo Sanabria, Michael Schlierf, Tim Schröder, Benjamin Schuler, Henning Seidel, Lisa Streit, Johann Thurn, Philip Tinnefeld, Swati Tyagi, Niels Vandenberk, Andrés Manuel Vera, Keith R. Weninger, Bettina Wünsch, Inna S. Yanez-Orozco, Jens Michaelis, Claus A. M. Seidel, Timothy D. Craggs & Thorsten Hugel.

Precision and accuracy of single-molecule FRET– a multi-laboratory benchmark study.

Nature Methods 15, 669–676 (2018). [pdf]

S. Schmid*, M. Götz & T. Hugel*.

Effects of Inhibitors on Hsp90’s Conformational Dynamics, Cochaperone and Client Interactions.

ChemPhysChem 19, 1716–1721 (2018). [pdf]

S. Schmid* & T. Hugel*.

Efficient use of single molecule time traces to resolve kinetic rates, models and uncertainties.

Journal of Chemical Physics 148, 123312 (2018). [pdf]

M. Götz, P. Wortmann, S. Schmid & T. Hugel.

A three-color single-molecule FRET approach to studying correlated interactions in the heat shock protein 90.

Journal of visualized experiments (JoVe) 131:e56896 (2018).

M. Götz, P. Wortmann, S. Schmid & T. Hugel.

A Multicolor Single-Molecule FRET Approach to Study Protein Dynamics and Interactions Simultaneously.

Methods in Enzymology. Ed. by Spies M, & Chemla YR. Vol. 581. Academic Press 487–516 (2016). [pdf]

S. Schmid, M. Götz & T. Hugel.

Single-Molecule Analysis beyond Dwell Times: Demonstration and Assessment in and out of Equilibrium.

Biophysical Journal 111, 7:1375–1384 (2016). [pdf]

S. Schmid & M. Götz. SMACKS Manual & Software. Online: [GitHub] www.singlemolecule.uni-freiburg.de/SMACKS (2016).

S. Schmid & T. Hugel.

Regulatory posttranslational modifications in Hsp90 can be compensated by cochaperone Aha1.

Molecular Cell 41, 6:619–620 (2010).